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ICDM
2007
IEEE
159views Data Mining» more  ICDM 2007»
13 years 11 months ago
Spectral Regression: A Unified Approach for Sparse Subspace Learning
Recently the problem of dimensionality reduction (or, subspace learning) has received a lot of interests in many fields of information processing, including data mining, informati...
Deng Cai, Xiaofei He, Jiawei Han
BMCBI
2010
128views more  BMCBI 2010»
13 years 7 months ago
Conserved residue clusters at protein-protein interfaces and their use in binding site identification
Background: Biological evolution conserves protein residues that are important for structure and function. Both protein stability and function often require a certain degree of st...
Mainak Guharoy, Pinak Chakrabarti
BIBE
2007
IEEE
124views Bioinformatics» more  BIBE 2007»
14 years 1 months ago
Finding Cancer-Related Gene Combinations Using a Molecular Evolutionary Algorithm
—High-throughput data such as microarrays make it possible to investigate the molecular-level mechanism of cancer more efficiently. Computational methods boost the microarray ana...
Chan-Hoon Park, Soo-Jin Kim, Sun Kim, Dong-Yeon Ch...
GCB
2009
Springer
139views Biometrics» more  GCB 2009»
13 years 11 months ago
Graph-Kernels for the Comparative Analysis of Protein Active Sites
Abstract: Graphs are often used to describe and analyze the geometry and physicochemical composition of biomolecular structures, such as chemical compounds and protein active sites...
Thomas Fober, Marco Mernberger, Ralph Moritz, Eyke...
BMCBI
2006
124views more  BMCBI 2006»
13 years 7 months ago
Detection of divergent genes in microbial aCGH experiments
Background: Array-based comparative genome hybridization (aCGH) is a tool for rapid comparison of genomes from different bacterial strains. The purpose of such analysis is to dete...
Lars Snipen, Dirk Repsilber, Ludvig Nyquist, &Arin...