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BMCBI
2006
128views more  BMCBI 2006»
13 years 9 months ago
Rank-statistics based enrichment-site prediction algorithm developed for chromatin immunoprecipitation on chip experiments
Background: High density oligonucleotide tiling arrays are an effective and powerful platform for conducting unbiased genome-wide studies. The ab initio probe selection method emp...
Srinka Ghosh, Heather A. Hirsch, Edward A. Sekinge...
BMCBI
2006
116views more  BMCBI 2006»
13 years 9 months ago
Optimized mixed Markov models for motif identification
Background: Identifying functional elements, such as transcriptional factor binding sites, is a fundamental step in reconstructing gene regulatory networks and remains a challengi...
Weichun Huang, David M. Umbach, Uwe Ohler, Leping ...
BMCBI
2006
113views more  BMCBI 2006»
13 years 9 months ago
GibbsST: a Gibbs sampling method for motif discovery with enhanced resistance to local optima
Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...
Kazuhito Shida
BMCBI
2006
86views more  BMCBI 2006»
13 years 9 months ago
Identification of QTLs controlling gene expression networks defined a priori
Background: Gene expression microarrays allow the quantification of transcript accumulation for many or all genes in a genome. This technology has been utilized for a range of inv...
Daniel J. Kliebenstein, Marilyn A. L. West, Hans v...
CCE
2006
13 years 9 months ago
State-of-the-art review of optimization methods for short-term scheduling of batch processes
There has been significant progress in the area of short-term scheduling of batch processes, including the solution of industrial-sized problems, in the last 20 years. The main go...
Carlos A. Méndez, Jaime Cerdá, Ignac...
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