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» Using probabilistic model checking in systems biology
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BIOINFORMATICS
2006
124views more  BIOINFORMATICS 2006»
13 years 9 months ago
Probabilistic inference of transcription factor concentrations and gene-specific regulatory activities
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Neil D. Lawrence, Magnus Rattra...
TACAS
2007
Springer
92views Algorithms» more  TACAS 2007»
14 years 3 months ago
Model Checking Liveness Properties of Genetic Regulatory Networks
Abstract. Recent studies have demonstrated the possibility to build genetic regulatory networks that confer a desired behavior to a living organism. However, the design of these ne...
Grégory Batt, Calin Belta, Ron Weiss
HICSS
2003
IEEE
99views Biometrics» more  HICSS 2003»
14 years 2 months ago
A probabilistic loading-dependent model of cascading failure and possible implications for blackouts
Catastrophic disruptions of large, interconnected infrastructure systems are often due to cascading failure. For example, large blackouts of electric power systems are typically c...
Ian Dobson, Benjamin A. Carreras, David E. Newman
CHARME
2001
Springer
105views Hardware» more  CHARME 2001»
14 years 1 months ago
Net Reductions for LTL Model-Checking
We present a set of reduction rules for LTL model-checking of 1-safe Petri nets. Our reduction techniques are of two kinds: (1) Linear programming techniques which are based on wel...
Javier Esparza, Claus Schröter
ISMB
1998
13 years 10 months ago
BioSim: A New Qualitative Simulation Environment for Molecular Biology
Traditionally, biochemical systems are modelled usingkinetics anddifferential equationsin a quantitative simulator. However,for manybiological processes detailed quantitative info...
Karsten R. Heidtke, Steffen Schulze-Kremer