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» Validating associations in biological databases
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BMCBI
2006
93views more  BMCBI 2006»
13 years 8 months ago
A summarization approach for Affymetrix GeneChip data using a reference training set from a large, biologically diverse database
Background: Many of the most popular pre-processing methods for Affymetrix expression arrays, such as RMA, gcRMA, and PLIER, simultaneously analyze data across a set of predetermi...
Simon Katz, Rafael A. Irizarry, Xue Lin, Mark Trip...
ICDM
2006
IEEE
127views Data Mining» more  ICDM 2006»
14 years 2 months ago
Predictive Integration of Gene Ontology-Driven Similarity and Functional Interactions
There is a need to develop methods to automatically incorporate prior knowledge to support the prediction and validation of novel functional associations. One such important sourc...
Francisco Azuaje, Haiying Wang, Huiru Zheng, Olivi...
ICCBR
2005
Springer
14 years 2 months ago
Knowledge Intensive Case Based Support for Automated Explanation of Biological Phenomena
The rapid growth of data stored in molecular biology-related databases has stimulated the development of integrative tools for retrieval and presentation of the data in the form of...
Waclaw Kusnierczyk, Agnar Aamodt, Astrid Læg...
BMCBI
2008
144views more  BMCBI 2008»
13 years 8 months ago
PDTD: a web-accessible protein database for drug target identification
Background: Target identification is important for modern drug discovery. With the advances in the development of molecular docking, potential binding proteins may be discovered b...
Zhenting Gao, Honglin Li, Hailei Zhang, Xiaofeng L...
TPDS
1998
112views more  TPDS 1998»
13 years 8 months ago
Parallel Computation in Biological Sequence Analysis
—A massive volume of biological sequence data is available in over 36 different databases worldwide, including the sequence data generated by the Human Genome project. These data...
Tieng K. Yap, Ophir Frieder, Robert L. Martino