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» Validating associations in biological databases
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BIOINFORMATICS
2008
203views more  BIOINFORMATICS 2008»
13 years 10 months ago
The SGN comparative map viewer
Background: A common approach to understanding the genetic basis of complex traits is through identification of associated quantitative trait loci (QTL). Fine mapping QTLs require...
Lukas A. Mueller, Adri A. Mills, Beth Skwarecki, R...
BMCBI
2008
115views more  BMCBI 2008»
13 years 10 months ago
PARPST: a PARallel algorithm to find peptide sequence tags
Background: Protein identification is one of the most challenging problems in proteomics. Tandem mass spectrometry provides an important tool to handle the protein identification ...
Sara Brunetti, Elena Lodi, Elisa Mori, Maria Stell...
ICDE
2010
IEEE
240views Database» more  ICDE 2010»
14 years 2 months ago
Top-K aggregation queries over large networks
Searching and mining large graphs today is critical to a variety of application domains, ranging from personalized recommendation in social networks, to searches for functional ass...
Xifeng Yan, Bin He, Feida Zhu, Jiawei Han
BMCBI
2010
160views more  BMCBI 2010»
13 years 10 months ago
Extracting consistent knowledge from highly inconsistent cancer gene data sources
Background: Hundreds of genes that are causally implicated in oncogenesis have been found and collected in various databases. For efficient application of these abundant but diver...
Xue Gong, Ruihong Wu, Yuannv Zhang, Wenyuan Zhao, ...
BIBM
2008
IEEE
217views Bioinformatics» more  BIBM 2008»
14 years 4 months ago
Combining Hierarchical Inference in Ontologies with Heterogeneous Data Sources Improves Gene Function Prediction
The study of gene function is critical in various genomic and proteomic fields. Due to the availability of tremendous amounts of different types of protein data, integrating thes...
Xiaoyu Jiang, Naoki Nariai, Martin Steffen, Simon ...