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» Validation Sequence Optimization: A Theoretical Approach
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BMCBI
2006
113views more  BMCBI 2006»
13 years 7 months ago
GibbsST: a Gibbs sampling method for motif discovery with enhanced resistance to local optima
Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...
Kazuhito Shida
SSIRI
2010
13 years 5 months ago
A Formal Framework for Mutation Testing
— Model-based approaches, especially based on directed graphs (DG), are becoming popular for mutation testing as they enable definition of simple, nevertheless powerful, mutation...
Fevzi Belli, Mutlu Beyazit
ICML
2008
IEEE
14 years 8 months ago
Dirichlet component analysis: feature extraction for compositional data
We consider feature extraction (dimensionality reduction) for compositional data, where the data vectors are constrained to be positive and constant-sum. In real-world problems, t...
Hua-Yan Wang, Qiang Yang, Hong Qin, Hongbin Zha
BMCBI
2005
79views more  BMCBI 2005»
13 years 7 months ago
Mathematical design of prokaryotic clone-based microarrays
Background: Clone-based microarrays, on which each spot represents a random genomic fragment, are a good alternative to open reading frame-based microarrays, especially for microo...
Bart Pieterse, Elisabeth J. Quirijns, Frank H. J. ...
BALT
2006
13 years 11 months ago
Introducing Softness into Inductive Queries on String Databases
In many application domains (e.g., WWW mining, molecular biology), large string datasets are available and yet under-exploited. The inductive database framework assumes that both s...
Ieva Mitasiunaite, Jean-François Boulicaut