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BMCBI
2010
13 years 7 months ago
2010
Background: DNA copy number aberration (CNA) is very important in the pathogenesis of tumors and other diseases. For example, CNAs may result in suppression of anti-oncogenes and ...
BMCBI
2010
13 years 7 months ago
2010
Background: Identifying disease gene from a list of candidate genes is an important task in bioinformatics. The main strategy is to prioritize candidate genes based on their simil...
BMCBI
2010
13 years 7 months ago
2010
Background: Type III secretion system (T3SS) is a specialized protein delivery system in gramnegative bacteria that injects proteins (called effectors) directly into the eukaryoti...
BMCBI
2008
13 years 7 months ago
2008
Background: The rate of mRNA transcription is controlled by transcription factors that bind to specific DNA motifs in promoter regions upstream of protein coding genes. Recent res...
BMCBI
2008
13 years 7 months ago
2008
Background: Recent genomic scale survey of epigenetic states in the mammalian genomes has shown that promoters and enhancers are correlated with distinct chromatin signatures, pro...