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BMCBI
2010
115views more  BMCBI 2010»
15 years 4 months ago
Importance of replication in analyzing time-series gene expression data: Corticosteroid dynamics and circadian patterns in rat l
Background: Microarray technology is a powerful and widely accepted experimental technique in molecular biology that allows studying genome wide transcriptional responses. However...
Tung T. Nguyen, Richard R. Almon, Debra C. DuBois,...
BMCBI
2008
128views more  BMCBI 2008»
15 years 4 months ago
Nonparametric relevance-shifted multiple testing procedures for the analysis of high-dimensional multivariate data with small sa
Background: In many research areas it is necessary to find differences between treatment groups with several variables. For example, studies of microarray data seek to find a sign...
Cornelia Frömke, Ludwig A. Hothorn, Siegfried...
BMCBI
2004
113views more  BMCBI 2004»
15 years 4 months ago
Oligo kernels for datamining on biological sequences: a case study on prokaryotic translation initiation sites
Background: Kernel-based learning algorithms are among the most advanced machine learning methods and have been successfully applied to a variety of sequence classification tasks ...
Peter Meinicke, Maike Tech, Burkhard Morgenstern, ...
EC
2012
289views ECommerce» more  EC 2012»
14 years 1 days ago
Multimodal Optimization Using a Bi-Objective Evolutionary Algorithm
In a multimodal optimization task, the main purpose is to find multiple optimal solutions (global and local), so that the user can have a better knowledge about different optima...
Kalyanmoy Deb, Amit Saha
GIS
2007
ACM
16 years 5 months ago
Proximity queries in large traffic networks
In this paper, we present an original network graph embedding to speed-up distance-range and k-nearest neighbor queries in (weighted) graphs. Our approach implements the paradigm ...
Hans-Peter Kriegel, Matthias Renz, Peer Kröge...