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BMCBI
2010
141views more  BMCBI 2010»
13 years 10 months ago
Genome scale prediction of substrate specificity for acyl adenylate superfamily of enzymes based on active site residue profiles
Background: Enzymes belonging to acyl:CoA synthetase (ACS) superfamily activate wide variety of substrates and play major role in increasing the structural and functional diversit...
Pankaj Khurana, Rajesh S. Gokhale, Debasisa Mohant...
BMCBI
2010
139views more  BMCBI 2010»
13 years 10 months ago
MOTIPS: Automated Motif Analysis for Predicting Targets of Modular Protein Domains
Background: Many protein interactions, especially those involved in signaling, involve short linear motifs consisting of 5-10 amino acid residues that interact with modular protei...
Hugo Y. K. Lam, Philip M. Kim, Janine Mok, Raffi T...
BMCBI
2008
95views more  BMCBI 2008»
13 years 10 months ago
Universal seeds for cDNA-to-genome comparison
Background: To meet the needs of gene annotation for newly sequenced organisms, optimized spaced seeds can be implemented into cross-species sequence alignment programs to accurat...
Leming Zhou, Jonathan Stanton, Liliana Florea
BMCBI
2008
74views more  BMCBI 2008»
13 years 10 months ago
Prediction of mucin-type O-glycosylation sites in mammalian proteins using the composition of k-spaced amino acid pairs
Background: As one of the most common protein post-translational modifications, glycosylation is involved in a variety of important biological processes. Computational identificat...
Yong-Zi Chen, Yu-Rong Tang, Zhi-Ya Sheng, Ziding Z...
COMCOM
2010
136views more  COMCOM 2010»
13 years 10 months ago
D-MORE: Dynamic mesh-based overlay peer-to-peer infrastructure
Traditionally, Internet Service Providers (ISPs) have to interconnect with content providers to provide network services to customers. The current business model that connectivity...
Jun Lei, Xiaoming Fu, Dieter Hogrefe