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BMCBI
2010
131views more  BMCBI 2010»
13 years 8 months ago
FACT: Functional annotation transfer between proteins with similar feature architectures
Background: The increasing number of sequenced genomes provides the basis for exploring the genetic and functional diversity within the tree of life. Only a tiny fraction of the e...
Tina Koestler, Arndt von Haeseler, Ingo Ebersberge...
BMCBI
2010
121views more  BMCBI 2010»
13 years 8 months ago
MS4 - Multi-Scale Selector of Sequence Signatures: An alignment-free method for classification of biological sequences
Background: While multiple alignment is the first step of usual classification schemes for biological sequences, alignment-free methods are being increasingly used as alternatives...
Eduardo Corel, Florian Pitschi, Ivan Laprevotte, G...
BMCBI
2008
145views more  BMCBI 2008»
13 years 8 months ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
BMCBI
2010
104views more  BMCBI 2010»
13 years 8 months ago
A method for automatically extracting infectious disease-related primers and probes from the literature
Background: Primer and probe sequences are the main components of nucleic acid-based detection systems. Biologists use primers and probes for different tasks, some related to the ...
Miguel García-Remesal, Alejandro Cuevas, Vi...
BMCBI
2008
125views more  BMCBI 2008»
13 years 8 months ago
SynteBase/SynteView: a tool to visualize gene order conservation in prokaryotic genomes
Background: It has been repeatedly observed that gene order is rapidly lost in prokaryotic genomes. However, persistent synteny blocks are found when comparing more or less distan...
Frédéric Lemoine, Bernard Labedan, O...