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BMCBI
2011
13 years 3 months ago
Using Stochastic Causal Trees to Augment Bayesian Networks for Modeling eQTL Datasets
Background: The combination of genotypic and genome-wide expression data arising from segregating populations offers an unprecedented opportunity to model and dissect complex phen...
Kyle C. Chipman, Ambuj K. Singh
BMCBI
2011
13 years 3 months ago
Context-dependent transcriptional regulations between signal transduction pathways
Background: Cells coordinate their metabolism, proliferation, and cellular communication according to environmental cues through signal transduction. Because signal transduction h...
Sohyun Hwang, Sangwoo Kim, Heesung Shin, Doheon Le...
BMCBI
2011
13 years 3 months ago
iPhy: an integrated phylogenetic workbench for supermatrix analyses
Background: The increasing availability of molecular sequence data means that the accuracy of future phylogenetic studies is likely to by limited by systematic bias and taxon choi...
Martin O. Jones, Georgios D. Koutsovoulos, Mark L....
BMCBI
2011
13 years 3 months ago
Removing Noise From Pyrosequenced Amplicons
Background: In many environmental genomics applications a homologous region of DNA from a diverse sample is first amplified by PCR and then sequenced. The next generation sequenci...
Christopher Quince, Anders Lanzén, Russell ...
BMCBI
2011
13 years 3 months ago
A lightweight, flow-based toolkit for parallel and distributed bioinformatics pipelines
Background: Bioinformatic analyses typically proceed as chains of data-processing tasks. A pipeline, or ‘workflow’, is a well-defined protocol, with a specific structure defin...
Marcin Cieslik, Cameron Mura
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