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BIOCOMP
2010
13 years 6 months ago
A Network-based Approach to Classify Disease Stages of Prostate Cancer Using Quantitative Network Measures
Abstract-- This study deals with investigating the classification performance of information-theoretic measures when applied to complex biological networks. In particular, our aim ...
Laurin A. J. Mueller, Karl G. Kugler, Andreas Dand...
ICMLA
2010
13 years 7 months ago
Smoothing Gene Expression Using Biological Networks
Gene expression (microarray) data have been used widely in bioinformatics. The expression data of a large number of genes from small numbers of subjects are used to identify inform...
Yue Fan, Mark A. Kon, Shinuk Kim, Charles DeLisi
TCBB
2011
13 years 4 months ago
Data Mining on DNA Sequences of Hepatitis B Virus
: Extraction of meaningful information from large experimental datasets is a key element of bioinformatics research. One of the challenges is to identify genomic markers in Hepatit...
Kwong-Sak Leung, Kin-Hong Lee, Jin Feng Wang, Eddi...
BMCBI
2006
146views more  BMCBI 2006»
13 years 10 months ago
Recursive gene selection based on maximum margin criterion: a comparison with SVM-RFE
Background: In class prediction problems using microarray data, gene selection is essential to improve the prediction accuracy and to identify potential marker genes for a disease...
Satoshi Niijima, Satoru Kuhara
BMCBI
2010
146views more  BMCBI 2010»
13 years 10 months ago
Nonnegative principal component analysis for mass spectral serum profiles and biomarker discovery
Background: As a novel cancer diagnostic paradigm, mass spectroscopic serum proteomic pattern diagnostics was reported superior to the conventional serologic cancer biomarkers. Ho...
Henry Han