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BIBE
2005
IEEE
14 years 3 months ago
Selecting Informative Genes from Microarray Dataset by Incorporating Gene Ontology
Selecting informative genes from microarray experiments is one of the most important data analysis steps for deciphering biological information imbedded in such experiments. Howev...
Xian Xu, Aidong Zhang
BMCBI
2008
106views more  BMCBI 2008»
13 years 10 months ago
SpliceCenter: A suite of web-based bioinformatic applications for evaluating the impact of alternative splicing on RT-PCR, RNAi,
Background: Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant chal...
Michael C. Ryan, Barry Zeeberg, Natasha J. Caplen,...
FLAIRS
2004
13 years 11 months ago
Gene Expression Data Classification with Revised Kernel Partial Least Squares Algorithm
One important feature of the gene expression data is that the number of genes M far exceeds the number of samples N. Standard statistical methods do not work well when N < M. D...
ZhenQiu Liu, Dechang Chen
WABI
2004
Springer
132views Bioinformatics» more  WABI 2004»
14 years 3 months ago
Joint Analysis of DNA Copy Numbers and Gene Expression Levels
Abstract. Genomic instabilities, amplifications, deletions and translocations are often observed in tumor cells. In the process of cancer pathogenesis cells acquire multiple genom...
Doron Lipson, Amir Ben-Dor, Elinor Dehan, Zohar Ya...
SADM
2010
173views more  SADM 2010»
13 years 4 months ago
Data reduction in classification: A simulated annealing based projection method
This paper is concerned with classifying high dimensional data into one of two categories. In various settings, such as when dealing with fMRI and microarray data, the number of v...
Tian Siva Tian, Rand R. Wilcox, Gareth M. James