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229
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BMCBI
2008
15 years 7 months ago
2008
Background: Biological signaling pathways that govern cellular physiology form an intricate web of tightly regulated interlocking processes. Data on these regulatory networks are ...
201
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BMCBI
2008
15 years 7 months ago
2008
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
184
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BMCBI
2008
15 years 7 months ago
2008
Background: An important aspect of proteomic mass spectrometry involves quantifying and interpreting the isotope distributions arising from mixtures of macromolecules with differe...
182
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BMCBI
2008
15 years 7 months ago
2008
teps. First, we abstracted protein interactions onto orthologous cluster links. For a given source interaction, if both proteins belonged to a cluster, we constructed a link betwee...
205
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BMCBI
2008
15 years 7 months ago
2008
Background: Research in life sciences is benefiting from a large availability of formal description techniques and analysis methodologies. These allow both the phenomena investiga...