-- Here the method proposed in [13] for constructing minimal-length checking sequences based on distinguishing sequences is improved. The improvement is based on optimizations of t...
Background: Structure-based computational methods are needed to help identify and characterize protein-protein complexes and their function. For individual proteins, the most succ...
In contrast to proteins, many classes of functionally related RNA molecules show a rather weak sequence conservation but instead a fairly well conserved secondary structure. Hence ...
Background: The conservation of gene order among prokaryotic genomes can provide valuable insight into gene function, protein interactions, or events by which genomes have evolved...
Christine Fong, Laurence Rohmer, Matthew Radey, Mi...
In this paper we present an approach that evolves the consensus sequence [25] for multiple sequence alignment (MSA) with genetic algorithm (GA). We have developed an encoding schem...