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BMCBI
2008
71views more  BMCBI 2008»
13 years 7 months ago
A tale of two symmetrical tails: Structural and functional characteristics of palindromes in proteins
Background: It has been previously shown that palindromic sequences are frequently observed in proteins. However, our knowledge about their evolutionary origin and their possible ...
Armita Sheari, Mehdi Kargar, Ali Katanforoush, Sha...
NAR
2006
120views more  NAR 2006»
13 years 7 months ago
TreeDomViewer: a tool for the visualization of phylogeny and protein domain structure
Phylogenetic analysis and examination of protein domains allow accurate genome annotation and are invaluable to study proteins and protein complex evolution. However, two sequence...
Blaise T. F. Alako, Daphne Rainey, Harm Nijveen, J...
BMCBI
2004
73views more  BMCBI 2004»
13 years 7 months ago
Use of a structural alphabet for analysis of short loops connecting repetitive structures
Background: Because loops connect regular secondary structures, analysis of the former depends directly on the definition of the latter. The numerous assignment methods, however, ...
Laurent Fourrier, Cristina Benros, Alexandre G. de...
BMCBI
2006
152views more  BMCBI 2006»
13 years 7 months ago
Predicting deleterious nsSNPs: an analysis of sequence and structural attributes
Background: There has been an explosion in the number of single nucleotide polymorphisms (SNPs) within public databases. In this study we focused on non-synonymous protein coding ...
Richard J. B. Dobson, Patricia B. Munroe, Mark J. ...
BMCBI
2010
107views more  BMCBI 2010»
13 years 2 months ago
Interaction prediction and classification of PDZ domains
Background: PDZ domain is a well-conserved, structural protein domain found in hundreds of signaling proteins that are otherwise unrelated. PDZ domains can bind to the C-terminal ...
Sibel Kalyoncu, Ozlem Keskin, Attila Gürsoy