A function of a protein is dependent on its structure; therefore, predicting a protein structure from an amino acid sequence is an active area of research. Optimally predicting a ...
Motivation: To test whether protein folding constraints and secondary structure sequence preferences significantly reduce the space of amino acid words in proteins, we compared th...
We present a novel method for predicting the secondary structure of a protein from its amino acid sequence. Most existing methods predict each position in turn based on a local wi...
Scott C. Schmidler, Jun S. Liu, Douglas L. Brutlag
Contact map prediction is of great interest for its application in fold recognition and protein 3D structure determination. In this paper we present a contact-map prediction algor...
Background: Prediction of transmembrane (TM) helices by statistical methods suffers from lack of sufficient training data. Current best methods use hundreds or even thousands of f...