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BMCBI
2010
143views more  BMCBI 2010»
13 years 7 months ago
An efficient biological pathway layout algorithm combining grid-layout and spring embedder for complicated cellular location inf
Background: Graph drawing is one of the important techniques for understanding biological regulations in a cell or among cells at the pathway level. Among many available layout al...
Kaname Kojima, Masao Nagasaki, Satoru Miyano
BMCBI
2008
226views more  BMCBI 2008»
13 years 7 months ago
ProteoLens: a visual analytic tool for multi-scale database-driven biological network data mining
Background: New systems biology studies require researchers to understand how interplay among myriads of biomolecular entities is orchestrated in order to achieve high-level cellu...
Tianxiao Huan, Andrey Y. Sivachenko, Scott H. Harr...
BMCBI
2010
135views more  BMCBI 2010»
13 years 7 months ago
Integration and visualization of systems biology data in context of the genome
Background: High-density tiling arrays and new sequencing technologies are generating rapidly increasing volumes of transcriptome and protein-DNA interaction data. Visualization a...
J. Christopher Bare, Tie Koide, David J. Reiss, Da...
BMCBI
2008
126views more  BMCBI 2008»
13 years 7 months ago
GeneChaser: Identifying all biological and clinical conditions in which genes of interest are differentially expressed
Background: The amount of gene expression data in the public repositories, such as NCBI Gene Expression Omnibus (GEO) has grown exponentially, and provides a gold mine for bioinfo...
Rong Chen, Rohan Mallelwar, Ajit Thosar, Shivkumar...
TMI
2008
149views more  TMI 2008»
13 years 7 months ago
Shape-Driven Three-Dimensional Watersnake Segmentation of Biological Membranes in Electron Tomography
Abstract--Due to the significant complexity of membrane morphology and the generally poor image quality in electron tomographic volumes, current automatic methods for segmentation ...
Hieu Tat Nguyen, Qiang Ji