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GECCO
2006
Springer
159views Optimization» more  GECCO 2006»
14 years 2 months ago
Identification of weak motifs in multiple biological sequences using genetic algorithm
Recognition of motifs in multiple unaligned sequences provides an insight into protein structure and function. The task of discovering these motifs is very challenging because mos...
Topon Kumar Paul, Hitoshi Iba
SDM
2003
SIAM
156views Data Mining» more  SDM 2003»
14 years 7 days ago
Detection of Underrepresented Biological Sequences using Class-Conditional Distribution Models
A labeled sequence data set related to a certain biological property is often biased and, therefore, does not completely capture its diversity in nature. To reduce this sampling b...
Slobodan Vucetic, Dragoljub Pokrajac, Hongbo Xie, ...
GECCO
2008
Springer
158views Optimization» more  GECCO 2008»
13 years 12 months ago
Structure and parameter estimation for cell systems biology models
In this work we present a new methodology for structure and parameter estimation in cell systems biology modelling. Our modelling framework is based on P systems, an unconl comput...
Francisco José Romero-Campero, Hongqing Cao...
EDBT
2004
ACM
230views Database» more  EDBT 2004»
14 years 11 months ago
Flexible Integration of Molecular-Biological Annotation Data: The GenMapper Approach
Molecular-biological annotation data is continuously being collected, curated and made accessible in numerous public data sources. Integration of this data is a major challenge in ...
Hong Hai Do, Erhard Rahm
GECCO
2007
Springer
168views Optimization» more  GECCO 2007»
14 years 5 months ago
Sex and death: towards biologically inspired heuristics for constraint handling
Constrained continuous optimization is still an interesting field of research. Many heuristics have been proposed in the last decade. Most of them are based on penalty functions....
Oliver Kramer, Stephan Brügger, Dejan Lazovic