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SCFBM
2008
87views more  SCFBM 2008»
15 years 4 months ago
Analysis by siRNA_profile program displays novel thermodynamic characteristics of highly functional siRNA molecules
Objective: Here we report the improved results of a new siRNA design program and analysis tool called siRNA_profile that reveals an additional criterion for bioinformatic search o...
Pirkko Muhonen, Ranga N. Parthasarathy, Anthony J....
MSR
2006
ACM
15 years 10 months ago
Using software birthmarks to identify similar classes and major functionalities
Software birthmarks are unique and native characteristics of every software component. Two components having similar birthmarks indicate that they are similar in functionality, st...
Takeshi Kakimoto, Akito Monden, Yasutaka Kamei, Ha...
PPSN
1992
Springer
15 years 8 months ago
Nonstationary Function Optimization using the Structured Genetic Algorithm
In this paper, we describe the application of a new type of genetic algorithm called the Structured Genetic Algorithm (sGA) for function optimization in nonstationary environments...
Dipankar Dasgupta, Douglas R. McGregor
GECCO
2008
Springer
174views Optimization» more  GECCO 2008»
15 years 5 months ago
Mask functions for the symbolic modeling of epistasis using genetic programming
The study of common, complex multifactorial diseases in genetic epidemiology is complicated by nonlinearity in the genotype-to-phenotype mapping relationship that is due, in part,...
Ryan J. Urbanowicz, Nate Barney, Bill C. White, Ja...
BMCBI
2006
118views more  BMCBI 2006»
15 years 4 months ago
Predicting the effect of missense mutations on protein function: analysis with Bayesian networks
Background: A number of methods that use both protein structural and evolutionary information are available to predict the functional consequences of missense mutations. However, ...
Chris J. Needham, James R. Bradford, Andrew J. Bul...