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BMCBI
2010
130views more  BMCBI 2010»
13 years 9 months ago
Knowledge-guided gene ranking by coordinative component analysis
Background: In cancer, gene networks and pathways often exhibit dynamic behavior, particularly during the process of carcinogenesis. Thus, it is important to prioritize those gene...
Chen Wang, Jianhua Xuan, Huai Li, Yue Wang, Ming Z...
BMCBI
2010
112views more  BMCBI 2010»
13 years 9 months ago
A parameter-adaptive dynamic programming approach for inferring cophylogenies
Background: Coevolutionary systems like hosts and their parasites are commonly used model systems for evolutionary studies. Inferring the coevolutionary history based on given phy...
Daniel Merkle, Martin Middendorf, Nicolas Wieseke
BMCBI
2010
92views more  BMCBI 2010»
13 years 9 months ago
HORI: a web server to compute Higher Order Residue Interactions in protein structures
Background: Folding of a protein into its three dimensional structure is influenced by both local and global interactions within a protein. Higher order residue interactions, like...
Pandurangan Sundaramurthy, Khader Shameer, Raashi ...
BMCBI
2010
104views more  BMCBI 2010»
13 years 9 months ago
Formal reasoning on qualitative models of coinfection of HIV and Tuberculosis and HAART therapy
Background: Several diseases, many of which nowadays pandemic, consist of multifactorial pathologies. Paradigmatic examples come from the immune response to pathogens, in which ca...
Anil Sorathiya, Andrea Bracciali, Pietro Liò...
BMCBI
2010
122views more  BMCBI 2010»
13 years 9 months ago
An automated framework for understanding structural variations in the binding grooves of MHC class II molecules
Background: MHC/HLA class II molecules are important components of the immune system and play a critical role in processes such as phagocytosis. Understanding peptide recognition ...
Kalidas Yeturu, Tapani Utriainen, Graham J. L. Kem...
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