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BMCBI
2006
126views more  BMCBI 2006»
13 years 9 months ago
A Regression-based K nearest neighbor algorithm for gene function prediction from heterogeneous data
Background: As a variety of functional genomic and proteomic techniques become available, there is an increasing need for functional analysis methodologies that integrate heteroge...
Zizhen Yao, Walter L. Ruzzo
BMCBI
2006
120views more  BMCBI 2006»
13 years 9 months ago
Projections for fast protein structure retrieval
Background: In recent times, there has been an exponential rise in the number of protein structures in databases e.g. PDB. So, design of fast algorithms capable of querying such d...
Sourangshu Bhattacharya, Chiranjib Bhattacharyya, ...
BMCBI
2006
165views more  BMCBI 2006»
13 years 9 months ago
Validation and functional annotation of expression-based clusters based on gene ontology
Background: The biological interpretation of large-scale gene expression data is one of the paramount challenges in current bioinformatics. In particular, placing the results in t...
Ralf Steuer, Peter Humburg, Joachim Selbig
BMCBI
2006
76views more  BMCBI 2006»
13 years 9 months ago
Coloring the Mu transpososome
Background: Tangle analysis has been applied successfully to study proteins which bind two segments of DNA and can knot and link circular DNA. We show how tangle analysis can be e...
Isabel K. Darcy, Jeff Chang, Nathan Druivenga, Col...
BMCBI
2006
106views more  BMCBI 2006»
13 years 9 months ago
Gene and protein nomenclature in public databases
Background: Frequently, several alternative names are in use for biological objects such as genes and proteins. Applications like manual literature search, automated text-mining, ...
Katrin Fundel, Ralf Zimmer
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