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BMCBI
2005
13 years 9 months ago
2005
Background: The functional sites of a protein present important information for determining its cellular function and are fundamental in drug design. Accordingly, accurate methods...
BMCBI
2005
13 years 9 months ago
2005
Background: Probabilistic models for sequence comparison (such as hidden Markov models and pair hidden Markov models for proteins and mRNAs, or their context-free grammar counterp...
BMCBI
2005
13 years 9 months ago
2005
Background: Normalization is a critical step in analysis of gene expression profiles. For duallabeled arrays, global normalization assumes that the majority of the genes on the ar...
BMCBI
2005
13 years 9 months ago
2005
Background: There has been tremendous interest in the study of biological network structure. An array of measurements has been conceived to assess the topological properties of th...
BMCBI
2005
13 years 9 months ago
2005
Background: Secondary structure is used in hierarchical classification of protein structures, identification of protein features, such as helix caps and loops, for fold recognitio...