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BMCBI
2010
103views more  BMCBI 2010»
15 years 2 months ago
Detecting internally symmetric protein structures
Background: Many functional proteins have a symmetric structure. Most of these are multimeric complexes, which are made of non-symmetric monomers arranged in a symmetric manner. H...
Changhoon Kim, Jodi Basner, Byungkook Lee
131
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BMCBI
2010
170views more  BMCBI 2010»
15 years 2 months ago
Integrative analysis of gene expression and copy number alterations using canonical correlation analysis
Background: With the rapid development of new genetic measurement methods, several types of genetic alterations can be quantified in a high-throughput manner. While the initial fo...
Charlotte Soneson, Henrik Lilljebjörn, Thoas ...
BMCBI
2010
134views more  BMCBI 2010»
15 years 2 months ago
Semi-automated screening of biomedical citations for systematic reviews
Background: Systematic reviews address a specific clinical question by unbiasedly assessing and analyzing the pertinent literature. Citation screening is a time-consuming and crit...
Byron C. Wallace, Thomas A. Trikalinos, Joseph Lau...
BIOSYSTEMS
2008
107views more  BIOSYSTEMS 2008»
15 years 2 months ago
The linearity of emergent spectro-temporal receptive fields in a model of auditory cortex
The responses of cortical neurons are often characterized by measuring their spectro-temporal receptive fields (strfs). The strf of a cell can be thought of as a representation of...
Martin Coath, Emili Balaguer-Ballester, Sue L. Den...
140
Voted
BMCBI
2010
189views more  BMCBI 2010»
15 years 2 months ago
Efficient parallel and out of core algorithms for constructing large bi-directed de Bruijn graphs
Background: Assembling genomic sequences from a set of overlapping reads is one of the most fundamental problems in computational biology. Algorithms addressing the assembly probl...
Vamsi Kundeti, Sanguthevar Rajasekaran, Hieu Dinh,...