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BMCBI
2005
116views more  BMCBI 2005»
13 years 7 months ago
Dynamic covariation between gene expression and proteome characteristics
Background: Cells react to changing intra- and extracellular signals by dynamically modulating complex biochemical networks. Cellular responses to extracellular signals lead to ch...
Mansour Taghavi Azar Sharabiani, Markku Siermala, ...
BMCBI
2005
112views more  BMCBI 2005»
13 years 7 months ago
Integration of the Gene Ontology into an object-oriented architecture
Background: To standardize gene product descriptions, a formal vocabulary defined as the Gene Ontology (GO) has been developed. GO terms have been categorized into biological proc...
Daniel Shegogue, W. Jim Zheng
BMCBI
2004
140views more  BMCBI 2004»
13 years 7 months ago
What can we learn from noncoding regions of similarity between genomes?
Background: In addition to known protein-coding genes, large amounts of apparently non-coding sequence are conserved between the human and mouse genomes. It seems reasonable to as...
Thomas A. Down, Tim J. P. Hubbard
BMCBI
2004
126views more  BMCBI 2004»
13 years 7 months ago
A probabilistic model for the evolution of RNA structure
Background: For the purposes of finding and aligning noncoding RNA gene- and cis-regulatory elements in multiple-genome datasets, it is useful to be able to derive multi-sequence ...
Ian Holmes
BMCBI
2004
149views more  BMCBI 2004»
13 years 7 months ago
MiCoViTo: a tool for gene-centric comparison and visualization of yeast transcriptome states
Background: Information obtained by DNA microarray technology gives a rough snapshot of the transcriptome state, i.e., the expression level of all the genes expressed in a cell po...
Gaëlle Lelandais, Philippe Marc, Pierre Vince...