Background: Several problems exist with current methods used to align DNA sequences for comparative sequence analysis. Most dynamic programming algorithms assume that conserved se...
Background: Profile hidden Markov model (HMM) techniques are among the most powerful methods for protein homology detection. Yet, the critical features for successful modelling ar...
Background: The application of high throughput approaches to the identification of protein interactions has offered for the first time a glimpse of the global interactome of some ...
Maria Persico, Arnaud Ceol, Caius Gavrila, Robert ...
Background: Our goal in BioCreAtIve has been to assess the state of the art in text mining, with emphasis on applications that reflect real biological applications, e.g., the cura...
Lynette Hirschman, Marc E. Colosimo, Alexander A. ...
Background: Multiple sequence alignment algorithms are very important tools in molecular biology today. Accurate alignment of proteins is central to several areas such as homology...
Saikat Chakrabarti, Nitin Bhardwaj, Prem A. Anand,...