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BMCBI
2010
85views more  BMCBI 2010»
13 years 10 months ago
Robust test method for time-course microarray experiments
Background: In a time-course microarray experiment, the expression level for each gene is observed across a number of time-points in order to characterize the temporal trajectorie...
Insuk Sohn, Kouros Owzar, Stephen L. George, Sujon...
BMCBI
2010
88views more  BMCBI 2010»
13 years 10 months ago
Robust probabilistic superposition and comparison of protein structures
Background: Protein structure comparison is a central issue in structural bioinformatics. The standard dissimilarity measure for protein structures is the root mean square deviati...
Martin Mechelke, Michael Habeck
BMCBI
2010
170views more  BMCBI 2010»
13 years 10 months ago
Analysis of lifestyle and metabolic predictors of visceral obesity with Bayesian Networks
Background: The aim of this study was to provide a framework for the analysis of visceral obesity and its determinants in women, where complex inter-relationships are observed amo...
Alex Aussem, André Tchernof, Sergio Rodrigu...
BMCBI
2010
124views more  BMCBI 2010»
13 years 10 months ago
Comparative analysis of acute and chronic corticosteroid pharmacogenomic effects in rat liver: Transcriptional dynamics and regu
Background: Comprehensively understanding corticosteroid pharmacogenomic effects is an essential step towards an insight into the underlying molecular mechanisms for both benefici...
Tung T. Nguyen, Richard R. Almon, Debra C. DuBois,...
BMCBI
2010
124views more  BMCBI 2010»
13 years 10 months ago
A factor model to analyze heterogeneity in gene expression
Background: Microarray technology allows the simultaneous analysis of thousands of genes within a single experiment. Significance analyses of transcriptomic data ignore the gene d...
Yuna Blum, Guillaume Le Mignon, Sandrine Lagarrigu...