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BMCBI
2006
13 years 10 months ago
2006
Background: The incorporation of statistical models that account for experimental variability provides a necessary framework for the interpretation of microarray data. A robust ex...
BMCBI
2006
13 years 10 months ago
2006
Background: High-density microarray technology is increasingly applied to study gene expression levels on a large scale. Microarray experiments rely on several critical steps that...
BMCBI
2006
13 years 10 months ago
2006
Background: Microarrays permit biologists to simultaneously measure the mRNA abundance of thousands of genes. An important issue facing investigators planning microarray experimen...
BMCBI
2006
13 years 10 months ago
2006
Background: Molecular evolutionary studies of noncoding sequences rely on multiple alignments. Yet how multiple alignment accuracy varies across sequence types, tree topologies, d...
BMCBI
2005
13 years 10 months ago
2005
Motivation: In cluster analysis, the validity of specific solutions, algorithms, and procedures present significant challenges because there is no null hypothesis to test and no &...