This article is a critical review of computational techniques used to model, analyse and simulate signalling networks. We propose a conceptual framework, and discuss the role of s...
One of the major goals of computational sequence analysis is to find sequence similarities, which could serve as evidence of structural and functional conservation, as well as of ...
The Biomolecular Interaction Network Database (BIND) (http://bind.ca) archives biomolecular interaction, reaction, complex and pathway information. Our aim is to curate the detail...
Much of biology works by applying prior knowledge (`what is known') to an unknown entity, rather than the application of a set of axioms that will elicit knowledge. In additi...
Flux balance analysis (FBA) has emerged as an effective means to analyse biological networks in a quantitative manner. Much progress has been made on the extension of FBA to incor...
Jong Min Lee, Erwin P. Gianchandani, Jason A. Papi...