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BIOINFORMATICS
2006
101views more  BIOINFORMATICS 2006»
13 years 9 months ago
A lock-and-key model for protein-protein interactions
Motivation: Protein-protein interaction networks are one of the major post-genomic data sources available to molecular biologists. They provide a comprehensive view of the global ...
Julie L. Morrison, Rainer Breitling, Desmond J. Hi...
BIOINFORMATICS
2006
120views more  BIOINFORMATICS 2006»
13 years 9 months ago
Comparison of Affymetrix GeneChip expression measures
Motivation: In the Affymetrix GeneChip system, preprocessing occurs before one obtains expression level measurements. Because the number of competing preprocessing methods was lar...
Rafael A. Irizarry, Zhijin Wu, Harris A. Jaffee
BIOINFORMATICS
2006
124views more  BIOINFORMATICS 2006»
13 years 9 months ago
Helix Interaction Tool (HIT): a web-based tool for analysis of helix-helix interactions in proteins
Motivation: In many proteins, helix-helix interactions can be critical to establishing protein conformation (folding) and dynamics, as well as determining associations between pro...
Anne E. Counterman Burba, Ursula Lehnert, Eric Z. ...
BIOINFORMATICS
2006
135views more  BIOINFORMATICS 2006»
13 years 9 months ago
Effective similarity measures for expression profiles
It is commonly accepted that genes with similar expression profiles are functionally related. However, there are many ways one can measure the similarity of expression profiles, a...
Golan Yona, William Dirks, Shafquat Rahman, David ...
BIOINFORMATICS
2005
169views more  BIOINFORMATICS 2005»
13 years 9 months ago
A statistical model providing comprehensive predictions for the mRNA differential display
s Dirk Tremmel, Maximilian Tropschug N. crassa FKBP22 is part of a protein folding helper complex in the ER [oral presentation] Manuela Heiner A carbamate-cleaving catalytic antibo...
David Meintrup, Ellen Reisinger