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BIOINFORMATICS
2005
109views more  BIOINFORMATICS 2005»
13 years 9 months ago
Prediction error estimation: a comparison of resampling methods
In genomic studies, thousands of features are collected on relatively few samples. One of the goals of these studies is to build classifiers to predict the outcome of future obser...
Annette M. Molinaro, Richard Simon, Ruth M. Pfeiff...
BIOINFORMATICS
2005
85views more  BIOINFORMATICS 2005»
13 years 9 months ago
An automated genotyping system for analysis of HIV-1 and other microbial sequences
Motivation: Genetic analysis of HIV-1 is important not only for vaccine development, but also to guide treatment strategies, track the emergence of new viral variants and ensure t...
Tulio de Oliveira, Koen Deforche, Sharon Cassol, M...
BIOINFORMATICS
2005
71views more  BIOINFORMATICS 2005»
13 years 9 months ago
Semi-supervised protein classification using cluster kernels
A key issue in supervised protein classification is the representation of input sequences of amino acids. Recent work using string kernels for protein data has achieved state-of-t...
Jason Weston, Christina S. Leslie, Eugene Ie, Deng...
BIOINFORMATICS
2004
83views more  BIOINFORMATICS 2004»
13 years 9 months ago
Haplotypes histories as pathways of recombinations
Motivation: The diversity of a haplotype, represented as a string of polymorphic sites along a DNA sequence, increases exponentially with the number of sites if recombinations are...
Nadia El-Mabrouk, Damian Labuda
BIOINFORMATICS
2004
99views more  BIOINFORMATICS 2004»
13 years 9 months ago
EST clustering error evaluation and correction
Motivation: The gene expression intensity information conveyed by (EST) Expressed Sequence Tag data can be used to infer important cDNA library properties, such as gene number and...
Ji-Ping Z. Wang, Bruce G. Lindsay 0002, James Leeb...