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BMCBI
2008
244views more  BMCBI 2008»
13 years 10 months ago
RNAalifold: improved consensus structure prediction for RNA alignments
Background: The prediction of a consensus structure for a set of related RNAs is an important first step for subsequent analyses. RNAalifold, which computes the minimum energy str...
Stephan H. F. Bernhart, Ivo L. Hofacker, Sebastian...
BMCBI
2008
95views more  BMCBI 2008»
13 years 10 months ago
Gene set analyses for interpreting microarray experiments on prokaryotic organisms
Background: Despite the widespread usage of DNA microarrays, questions remain about how best to interpret the wealth of gene-by-gene transcriptional levels that they measure. Rece...
Nathan L. Tintle, Aaron A. Best, Matthew DeJongh, ...
BMCBI
2008
124views more  BMCBI 2008»
13 years 10 months ago
Literature-aided meta-analysis of microarray data: a compendium study on muscle development and disease
Background: Comparative analysis of expression microarray studies is difficult due to the large influence of technical factors on experimental outcome. Still, the identified diffe...
Rob Jelier, Peter A. C. 't Hoen, Ellen Sterrenburg...
BMCBI
2008
98views more  BMCBI 2008»
13 years 10 months ago
Normalization of Illumina Infinium whole-genome SNP data improves copy number estimates and allelic intensity ratios
Background: Illumina Infinium whole genome genotyping (WGG) arrays are increasingly being applied in cancer genomics to study gene copy number alterations and allele-specific aber...
Johan Staaf, Johan Vallon-Christersson, David Lind...
CIBCB
2009
IEEE
13 years 11 months ago
Improved prediction of trans-membrane spans in proteins using an artificial neural network
Tools for the identification of trans-membrane spans from the protein sequence are widely used in the experimental community. Computational structural biology seeks to increase the...
Julia Koehler, Ralf Mueller, Jens Meiler