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WABI
2010
Springer
177views Bioinformatics» more  WABI 2010»
13 years 8 months ago
Estimation of Alternative Splicing isoform Frequencies from RNA-Seq Data
In this paper we present a novel expectation-maximization algorithm for inference of alternative splicing isoform frequencies from high-throughput transcriptome sequencing (RNA-Seq...
Marius Nicolae, Serghei Mangul, Ion I. Mandoiu, Al...
HPDC
2010
IEEE
13 years 11 months ago
Optimization of a parallel permutation testing function for the SPRINT R package
The statistical language R and Bioconductor package are favoured by many biostatisticians for processing microarray data. The amount of data produced by these analyses has reached...
Savvas Petrou, Terence M. Sloan, Muriel Mewissen, ...
WABI
2010
Springer
172views Bioinformatics» more  WABI 2010»
13 years 8 months ago
Fast Mapping and Precise Alignment of AB SOLiD Color Reads to Reference DNA
Abstract. Applied Biosystems’ SOLiD system offers a low-cost alternative to the traditional Sanger method of DNA sequencing. We introduce two main algorithms of mapping SOLiD’...
Miklós Csürös, Szilveszter Juhos,...
ISBRA
2010
Springer
13 years 7 months ago
Residue Contexts: Non-sequential Protein Structure Alignment Using Structural and Biochemical Features
The study of non-sequential alignments, with different connectivity of the aligned fragments in the proteins being compared can offer a more complete picture of the structural, evo...
Jay W. Kim, Rahul Singh
BMCBI
2010
175views more  BMCBI 2010»
13 years 10 months ago
The BridgeDb framework: standardized access to gene, protein and metabolite identifier mapping services
Background: Many complementary solutions are available for the identifier mapping problem. This creates an opportunity for bioinformatics tool developers. Tools can be made to fle...
Martijn P. van Iersel, Alexander R. Pico, Thomas K...