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BIOCOMP
2010
13 years 8 months ago
Extraction of Protein Sequence Motifs Information by Bi-Clustering Algorithm
- The activities and function of proteins can potentially be determined by protein sequence motifs. Therefore, obtaining the universally conserved and crossed protein family bounda...
Vincent Yip, Bernard Chen, Sinan Kockara
PRIB
2010
Springer
192views Bioinformatics» more  PRIB 2010»
13 years 8 months ago
Structured Output Prediction of Anti-cancer Drug Activity
We present a structured output prediction approach for classifying potential anti-cancer drugs. Our QSAR model takes as input a description of a molecule and predicts the activity...
Hongyu Su, Markus Heinonen, Juho Rousu
PRIB
2010
Springer
123views Bioinformatics» more  PRIB 2010»
13 years 8 months ago
Machine Learning Study of DNA Binding by Transcription Factors from the LacI Family
We studied 1372 LacI-family transcription factors and their 4484 DNA binding sites using machine learning algorithms and feature selection techniques. The Naive Bayes classifier a...
Gennady G. Fedonin, Mikhail S. Gelfand
WABI
2010
Springer
143views Bioinformatics» more  WABI 2010»
13 years 8 months ago
Swiftly Computing Center Strings
The center string (or closest string) problem is a classical computer science problem with important applications in computational biology. Given k input strings and a distance thr...
Franziska Hufsky, Léon Kuchenbecker, Kathar...
WABI
2010
Springer
160views Bioinformatics» more  WABI 2010»
13 years 8 months ago
Genomic Distance with DCJ and Indels
The double cut and join (DCJ) operation, introduced by Yancopoulos, Attie and Friedberg in 2005, allows one to represent most rearrangement events in genomes. However, a DCJ cannot...
Marília D. V. Braga, Eyla Willing, Jens Sto...