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BMCBI
2005
99views more  BMCBI 2005»
13 years 11 months ago
Super paramagnetic clustering of protein sequences
Background: Detection of sequence homologues represents a challenging task that is important for the discovery of protein families and the reliable application of automatic annota...
Igor V. Tetko, Axel Facius, Andreas Ruepp, Hans-We...
BMCBI
2005
94views more  BMCBI 2005»
13 years 11 months ago
Workflows in bioinformatics: meta-analysis and prototype implementation of a workflow generator
Background: Computational methods for problem solving need to interleave information access and algorithm execution in a problem-specific workflow. The structures of these workflo...
Alexander García Castro, Samuel Thoraval, L...
BMCBI
2005
63views more  BMCBI 2005»
13 years 11 months ago
Individual sequences in large sets of gene sequences may be distinguished efficiently by combinations of shared sub-sequences
Background: Most current DNA diagnostic tests for identifying organisms use specific oligonucleotide probes that are complementary in sequence to, and hence only hybridise with th...
Mark J. Gibbs, John S. Armstrong, Adrian J. Gibbs
BMCBI
2005
114views more  BMCBI 2005»
13 years 11 months ago
Quality determination and the repair of poor quality spots in array experiments
Background: A common feature of microarray experiments is the occurence of missing gene expression data. These missing values occur for a variety of reasons, in particular, becaus...
Brian D. M. Tom, Walter R. Gilks, Elizabeth T. Bro...
BMCBI
2006
125views more  BMCBI 2006»
13 years 11 months ago
Algebraic comparison of metabolic networks, phylogenetic inference, and metabolic innovation
Metabolic networks are naturally represented as directed hypergraphs in such a way that metabolites are nodes and enzyme-catalyzed reactions form (hyper)edges. The familiar operat...
Christian V. Forst, Christoph Flamm, Ivo L. Hofack...