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BMCBI
2005
180views more  BMCBI 2005»
13 years 11 months ago
arrayCGHbase: an analysis platform for comparative genomic hybridization microarrays
Background: The availability of the human genome sequence as well as the large number of physically accessible oligonucleotides, cDNA, and BAC clones across the entire genome has ...
Björn Menten, Filip Pattyn, Katleen De Preter...
BMCBI
2005
135views more  BMCBI 2005»
13 years 11 months ago
A robust two-way semi-linear model for normalization of cDNA microarray data
Background: Normalization is a basic step in microarray data analysis. A proper normalization procedure ensures that the intensity ratios provide meaningful measures of relative e...
Deli Wang, Jian Huang, Hehuang Xie, Liliana Manzel...
BMCBI
2005
137views more  BMCBI 2005»
13 years 11 months ago
A configuration space of homologous proteins conserving mutual information and allowing a phylogeny inference based on pair-wise
Background: Popular methods to reconstruct molecular phylogenies are based on multiple sequence alignments, in which addition or removal of data may change the resulting tree topo...
Olivier Bastien, Philippe Ortet, Sylvaine Roy, Eri...
BMCBI
2005
104views more  BMCBI 2005»
13 years 11 months ago
An integrated approach of immunogenomics and bioinformatics to identify new Tumor Associated Antigens (TAA) for mammary cancer i
Background: Neoplastic transformation is a multistep process in which distinct gene products of specific cell regulatory pathways are involved at each stage. Identification of ove...
Federica Cavallo, Annalisa Astolfi, Manuela Iezzi,...
BMCBI
2005
117views more  BMCBI 2005»
13 years 11 months ago
HmtDB, a Human Mitochondrial Genomic Resource Based on Variability Studies Supporting Population Genetics and Biomedical Researc
Background: Population genetics studies based on the analysis of mtDNA and mitochondrial disease studies have produced a huge quantity of sequence data and related information. Th...
Marcella Attimonelli, Matteo Accetturo, Monica San...