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BMCBI
2005
13 years 11 months ago
2005
Background: The functional sites of a protein present important information for determining its cellular function and are fundamental in drug design. Accordingly, accurate methods...
BMCBI
2005
13 years 11 months ago
2005
Background: A large number of papers have been published on analysis of microarray data with particular emphasis on normalization of data, detection of differentially expressed ge...
BMCBI
2005
13 years 11 months ago
2005
Background: Quality-control is an important issue in the analysis of gene expression microarrays. One type of problem is regional bias, in which one region of a chip shows artifac...
BMCBI
2005
13 years 11 months ago
2005
Background: To study complex biochemical reaction networks in living cells researchers more and more rely on databases and computational methods. In order to facilitate computatio...
BMCBI
2005
13 years 11 months ago
2005
Background: Expressed Sequence Tags (ESTs) are short and error-prone DNA sequences generated from the 5' and 3' ends of randomly selected cDNA clones. They provide an im...