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BMCBI
2005
90views more  BMCBI 2005»
13 years 10 months ago
TMB-Hunt: An amino acid composition based method to screen proteomes for beta-barrel transmembrane proteins
Background: Beta-barrel transmembrane (bbtm) proteins are a functionally important and diverse group of proteins expressed in the outer membranes of bacteria (both gram negative a...
Andrew G. Garrow, Alison Agnew, David R. Westhead
BMCBI
2005
126views more  BMCBI 2005»
13 years 10 months ago
Integrative analysis of multiple gene expression profiles with quality-adjusted effect size models
Background: With the explosion of microarray studies, an enormous amount of data is being produced. Systematic integration of gene expression data from different sources increases...
Pingzhao Hu, Celia M. T. Greenwood, Joseph Beyene
BMCBI
2005
121views more  BMCBI 2005»
13 years 10 months ago
Automated methods of predicting the function of biological sequences using GO and BLAST
Background: With the exponential increase in genomic sequence data there is a need to develop automated approaches to deducing the biological functions of novel sequences with hig...
Craig E. Jones, Ute Baumann, Alfred L. Brown
BMCBI
2005
82views more  BMCBI 2005»
13 years 10 months ago
A novel method for prokaryotic promoter prediction based on DNA stability
Background: In the post-genomic era, correct gene prediction has become one of the biggest challenges in genome annotation. Improved promoter prediction methods can be one step to...
Aditi Kanhere, Manju Bansal
BMCBI
2005
149views more  BMCBI 2005»
13 years 10 months ago
The PD-(D/E)XK superfamily revisited: identification of new members among proteins involved in DNA metabolism and functional pre
Background: The PD-(D/E)XK nuclease superfamily, initially identified in type II restriction endonucleases and later in many enzymes involved in DNA recombination and repair, is o...
Jan Kosinski, Marcin Feder, Janusz M. Bujnicki