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BMCBI
2005
198views more  BMCBI 2005»
13 years 10 months ago
Clustering protein sequences with a novel metric transformed from sequence similarity scores and sequence alignments with neural
Background: The sequencing of the human genome has enabled us to access a comprehensive list of genes (both experimental and predicted) for further analysis. While a majority of t...
Qicheng Ma, Gung-Wei Chirn, Richard Cai, Joseph D....
BMCBI
2005
87views more  BMCBI 2005»
13 years 10 months ago
Efficient decoding algorithms for generalized hidden Markov model gene finders
Background: The Generalized Hidden Markov Model (GHMM) has proven a useful framework for the task of computational gene prediction in eukaryotic genomes, due to its flexibility an...
William H. Majoros, Mihaela Pertea, Arthur L. Delc...
BMCBI
2005
94views more  BMCBI 2005»
13 years 10 months ago
T.I.M.S: TaqMan Information Management System, tools to organize data flow in a genotyping laboratory
Background: Single Nucleotide Polymorphism (SNP) genotyping is a major activity in biomedical research. The Taqman technology is one of the most commonly used approaches. It produ...
Stéphanie Monnier, David G. Cox, Tim Albion...
BMCBI
2005
93views more  BMCBI 2005»
13 years 10 months ago
Two-part permutation tests for DNA methylation and microarray data
Background: One important application of microarray experiments is to identify differentially expressed genes. Often, small and negative expression levels were clipped-off to be e...
Markus Neuhäuser, Tanja Boes, Karl-Heinz J&ou...
BMCBI
2005
107views more  BMCBI 2005»
13 years 10 months ago
An edit script for taxonomic classifications
Abstract. Taxonomy provides one of the most powerful ways to navigate sequence data bases but currently, users are forced to formulate queries according to a single taxonomic class...
Roderic D. M. Page, Gabriel Valiente