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    BMCBI
    2005
    108views more  BMCBI 2005»
    The modeled structure of the RNA dependent RNA polymerase of GBV-C Virus suggests a role for motif E in Flaviviridae RNA polymer
    13 years 9 months ago
    The modeled structure of the RNA dependent RNA polymerase of GBV-C Virus suggests a role for motif E in Flaviviridae RNA polymer
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    Background: The Flaviviridae virus family includes major human and animal pathogens. The RNA dependent RNA polymerase (RdRp) plays a central role in the replication process, and t...
    François Ferron, Cécile Bussetta, H&...
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    BMCBI
    2005
    136views more  BMCBI 2005»
    Identification of clustered microRNAs using an ab initio prediction method
    13 years 9 months ago
    Identification of clustered microRNAs using an ab initio prediction method
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    Background: MicroRNAs (miRNAs) are endogenous 21 to 23-nucleotide RNA molecules that regulate protein-coding gene expression in plants and animals via the RNA interference pathway...
    Alain Sewer, Nicodème Paul, Pablo Landgraf,...
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    BMCBI
    2005
    121views more  BMCBI 2005»
    Comparison of seven methods for producing Affymetrix expression scores based on False Discovery Rates in disease profiling data
    13 years 9 months ago
    Comparison of seven methods for producing Affymetrix expression scores based on False Discovery Rates in disease profiling data
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    Background: A critical step in processing oligonucleotide microarray data is combining the information in multiple probes to produce a single number that best captures the express...
    Kerby Shedden, Wei Chen, Rork Kuick, Debashis Ghos...
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    BMCBI
    2005
    143views more  BMCBI 2005»
    Gene capture prediction and overlap estimation in EST sequencing from one or multiple libraries
    13 years 9 months ago
    Gene capture prediction and overlap estimation in EST sequencing from one or multiple libraries
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    Background: In expressed sequence tag (EST) sequencing, we are often interested in how many genes we can capture in an EST sample of a targeted size. This information provides ins...
    Ji-Ping Z. Wang, Bruce G. Lindsay 0002, Liying Cui...
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    BMCBI
    2005
    223views more  BMCBI 2005»
    Bioinformatics approaches for cross-species liver cancer analysis based on microarray gene expression profiling
    13 years 9 months ago
    Bioinformatics approaches for cross-species liver cancer analysis based on microarray gene expression profiling
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    Background: The completion of the sequencing of human, mouse and rat genomes and knowledge of cross-species gene homologies enables studies of differential gene expression in anim...
    Hong Fang, Weida Tong, Roger Perkins, Leming M. Sh...
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