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BMCBI
2008
128views more  BMCBI 2008»
13 years 9 months ago
HAPSIMU: a genetic simulation platform for population-based association studies
Background: Population structure is an important cause leading to inconsistent results in population-based association studies (PBAS) of human diseases. Various statistical method...
Feng Zhang, Jianfeng Liu, Jie Chen, Hong-Wen Deng
BMCBI
2008
323views more  BMCBI 2008»
13 years 9 months ago
A compatible exon-exon junction database for the identification of exon skipping events using tandem mass spectrum data
Background: Alternative splicing is an important gene regulation mechanism. It is estimated that about 74% of multi-exon human genes have alternative splicing. High throughput tan...
Fan Mo, Xu Hong, Feng Gao, Lin Du, Jun Wang, Gilbe...
BMCBI
2008
94views more  BMCBI 2008»
13 years 9 months ago
Identification of Proteins Secreted by Malaria Parasite into Erythrocyte using SVM and PSSM profiles
Background: Malaria parasite secretes various proteins in infected RBC for its growth and survival. Thus identification of these secretory proteins is important for developing vac...
Ruchi Verma, Ajit Tiwari, Sukhwinder Kaur, Grish C...
BMCBI
2008
110views more  BMCBI 2008»
13 years 9 months ago
Predikin and PredikinDB: a computational framework for the prediction of protein kinase peptide specificity and an associated da
Background: We have previously described an approach to predicting the substrate specificity of serine-threonine protein kinases. The method, named Predikin, identifies key conser...
Neil F. W. Saunders, Ross I. Brinkworth, Thomas Hu...
BMCBI
2008
135views more  BMCBI 2008»
13 years 9 months ago
Using Generalized Procrustes Analysis (GPA) for normalization of cDNA microarray data
Background: Normalization is essential in dual-labelled microarray data analysis to remove nonbiological variations and systematic biases. Many normalization methods have been use...
Huiling Xiong, Dapeng Zhang, Christopher J. Martyn...