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BMCBI
2008
99views more  BMCBI 2008»
13 years 9 months ago
CWRML: representing crop wild relative conservation and use data in XML
Background: Crop wild relatives are wild species that are closely related to crops. They are valuable as potential gene donors for crop improvement and may help to ensure food sec...
Jonathan D. Moore, Shelagh P. Kell, Jose M. Iriond...
BMCBI
2008
104views more  BMCBI 2008»
13 years 9 months ago
Comparison of methods for estimating the nucleotide substitution matrix
Background: The nucleotide substitution rate matrix is a key parameter of molecular evolution. Several methods for inferring this parameter have been proposed, with different math...
Maribeth Oscamou, Daniel McDonald, Von Bing Yap, G...
BMCBI
2008
138views more  BMCBI 2008»
13 years 9 months ago
Methods for simultaneously identifying coherent local clusters with smooth global patterns in gene expression profiles
Background: The hierarchical clustering tree (HCT) with a dendrogram [1] and the singular value decomposition (SVD) with a dimension-reduced representative map [2] are popular met...
Yin-Jing Tien, Yun-Shien Lee, Han-Ming Wu, Chun-Ho...
BMCBI
2008
120views more  BMCBI 2008»
13 years 9 months ago
Statistical issues in the analysis of Illumina data
Background: Illumina bead-based arrays are becoming increasingly popular due to their high degree of replication and reported high data quality. However, little attention has been...
Mark J. Dunning, Nuno L. Barbosa-Morais, Andy G. L...
BMCBI
2008
160views more  BMCBI 2008»
13 years 9 months ago
A comparison of four clustering methods for brain expression microarray data
Background: DNA microarrays, which determine the expression levels of tens of thousands of genes from a sample, are an important research tool. However, the volume of data they pr...
Alexander L. Richards, Peter Holmans, Michael C. O...