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BMCBI
2008
138views more  BMCBI 2008»
13 years 9 months ago
Application of nonnegative matrix factorization to improve profile-profile alignment features for fold recognition and remote ho
Background: Nonnegative matrix factorization (NMF) is a feature extraction method that has the property of intuitive part-based representation of the original features. This uniqu...
Inkyung Jung, Jaehyung Lee, Soo-Young Lee, Dongsup...
BMCBI
2008
119views more  BMCBI 2008»
13 years 9 months ago
Integrated multi-level quality control for proteomic profiling studies using mass spectrometry
Background: Proteomic profiling using mass spectrometry (MS) is one of the most promising methods for the analysis of complex biological samples such as urine, serum and tissue fo...
David A. Cairns, David N. Perkins, Anthea J. Stanl...
BMCBI
2008
119views more  BMCBI 2008»
13 years 9 months ago
Gene Ontology density estimation and discourse analysis for automatic GeneRiF extraction
Background: This paper describes and evaluates a sentence selection engine that extracts a GeneRiF (Gene Reference into Functions) as defined in ENTREZ-Gene based on a MEDLINE rec...
Julien Gobeill, Imad Tbahriti, Frédé...
BMCBI
2008
96views more  BMCBI 2008»
13 years 9 months ago
Mapping proteins to disease terminologies: from UniProt to MeSH
Background: Although the UniProt KnowledgeBase is not a medical-oriented database, it contains information on more than 2,000 human proteins involved in pathologies. However, thes...
Anaïs Mottaz, Yum Lina Yip, Patrick Ruch, Ann...
BMCBI
2008
115views more  BMCBI 2008»
13 years 9 months ago
BioGraphE: high-performance bionetwork analysis using the Biological Graph Environment
Background: Graphs and networks are common analysis representations for biological systems. Many traditional graph algorithms such as k-clique, k-coloring, and subgraph matching h...
George Chin Jr., Daniel G. Chavarría-Mirand...