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BMCBI
2008
107views more  BMCBI 2008»
13 years 8 months ago
RIPCAL: a tool for alignment-based analysis of repeat-induced point mutations in fungal genomic sequences
Background: Repeat-induced point mutation (RIP) is a fungal-specific genome defence mechanism that alters the sequences of repetitive DNA, thereby inactivating coding genes. Repea...
James K. Hane, Richard P. Oliver
BMCBI
2008
67views more  BMCBI 2008»
13 years 8 months ago
Modeling Escherichia coli signal peptidase complex with bound substrate: determinants in the mature peptide influencing signal p
Background: Type I signal peptidases (SPases) are essential membrane-bound serine proteases responsible for the cleavage of signal peptides from proteins that are translocated acr...
Khar Heng Choo, Joo Chuan Tong, Shoba Ranganathan
BMCBI
2008
111views more  BMCBI 2008»
13 years 8 months ago
Distinguishing the species of biomedical named entities for term identification
Background: Term identification is the task of grounding ambiguous mentions of biomedical named entities in text to unique database identifiers. Previous work on term identificati...
Xinglong Wang, Michael Matthews
BMCBI
2008
99views more  BMCBI 2008»
13 years 8 months ago
Highlights from the Fourth International Society for Computational Biology Student Council Symposium at the Sixteenth Annual Int
In this meeting report we give an overview of the talks and presentations from the Fourth International Society for Computational Biology (ISCB) Student Council Symposium held as ...
Lucia Peixoto, Nils Gehlenborg, Sarath Chandra Jan...
BMCBI
2008
100views more  BMCBI 2008»
13 years 8 months ago
Extracting transcription factor binding sites from unaligned gene sequences with statistical models
Background: Transcription factor binding sites (TFBSs) are crucial in the regulation of gene transcription. Recently, chromatin immunoprecipitation followed by cDNA microarray hyb...
Chung-Chin Lu, Wei-Hao Yuan, Te-Ming Chen