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BMCBI
2008
111views more  BMCBI 2008»
13 years 8 months ago
CBESW: Sequence Alignment on the Playstation 3
Background: The exponential growth of available biological data has caused bioinformatics to be rapidly moving towards a data-intensive, computational science. As a result, the co...
Adrianto Wirawan, Chee Keong Kwoh, Nim Tri Hieu, B...
BMCBI
2008
58views more  BMCBI 2008»
13 years 8 months ago
Recovering probabilities for nucleotide trimming processes for T cell receptor TRA and TRG V-J junctions analyzed with IMGT tool
Background: Nucleotides are trimmed from the ends of variable (V), diversity (D) and joining (J) genes during immunoglobulin (IG) and T cell receptor (TR) rearrangements in B cell...
Kevin Bleakley, Marie-Paule Lefranc, Gérard...
BMCBI
2008
87views more  BMCBI 2008»
13 years 8 months ago
Global rank-invariant set normalization (GRSN) to reduce systematic distortions in microarray data
Background: Microarray technology has become very popular for globally evaluating gene expression in biological samples. However, non-linear variation associated with the technolo...
Carl R. Pelz, Molly Kulesz-Martin, Grover Bagby, R...
BMCBI
2008
99views more  BMCBI 2008»
13 years 8 months ago
Comparative phyloinformatics of virus genes at micro and macro levels in a distributed computing environment
Background: Preparedness for a possible global pandemic caused by viruses such as the highly pathogenic influenza A subtype H5N1 has become a global priority. In particular, it is...
Dadabhai T. Singh, Rahul Trehan, Bertil Schmidt, T...
BMCBI
2008
117views more  BMCBI 2008»
13 years 8 months ago
Cascaded classifiers for confidence-based chemical named entity recognition
Chemical named entities represent an important facet of biomedical text. We have developed a system to use character-based ngrams, Maximum Entropy Markov Models and rescoring to r...
Peter Corbett, Ann A. Copestake