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BMCBI
2008
154views more  BMCBI 2008»
13 years 8 months ago
Sequence based residue depth prediction using evolutionary information and predicted secondary structure
Background: Residue depth allows determining how deeply a given residue is buried, in contrast to the solvent accessibility that differentiates between buried and solvent-exposed ...
Hua Zhang, Tuo Zhang, Ke Chen 0003, Shiyi Shen, Ji...
BMCBI
2008
105views more  BMCBI 2008»
13 years 8 months ago
Objective and automated protocols for the evaluation of biomedical search engines using No Title Evaluation protocols
Background: The evaluation of information retrieval techniques has traditionally relied on human judges to determine which documents are relevant to a query and which are not. Thi...
Fabien Campagne
BMCBI
2008
93views more  BMCBI 2008»
13 years 8 months ago
VirulentPred: a SVM based prediction method for virulent proteins in bacterial pathogens
Background: Prediction of bacterial virulent protein sequences has implications for identification and characterization of novel virulence-associated factors, finding novel drug/v...
Aarti Garg, Dinesh Gupta
BMCBI
2008
95views more  BMCBI 2008»
13 years 8 months ago
Universal seeds for cDNA-to-genome comparison
Background: To meet the needs of gene annotation for newly sequenced organisms, optimized spaced seeds can be implemented into cross-species sequence alignment programs to accurat...
Leming Zhou, Jonathan Stanton, Liliana Florea
BMCBI
2008
111views more  BMCBI 2008»
13 years 8 months ago
MLIP: using multiple processors to compute the posterior probability of linkage
Background: Localization of complex traits by genetic linkage analysis may involve exploration of a vast multidimensional parameter space. The posterior probability of linkage (PP...
Manika Govil, Alberto Maria Segre, Veronica J. Vie...