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BMCBI
2008
211views more  BMCBI 2008»
13 years 8 months ago
CPSP-tools - Exact and complete algorithms for high-throughput 3D lattice protein studies
Background: The principles of protein folding and evolution pose problems of very high inherent complexity. Often these problems are tackled using simplified protein models, e.g. ...
Martin Mann, Sebastian Will, Rolf Backofen
BMCBI
2008
97views more  BMCBI 2008»
13 years 8 months ago
Large-scale directional relationship extraction and resolution
Background: Relationships between entities such as genes, chemicals, metabolites, phenotypes and diseases in MEDLINE are often directional. That is, one may affect the other in a ...
Cory B. Giles, Jonathan D. Wren
BMCBI
2008
77views more  BMCBI 2008»
13 years 8 months ago
Stochastic models for the in silico simulation of synaptic processes
Background: Research in life sciences is benefiting from a large availability of formal description techniques and analysis methodologies. These allow both the phenomena investiga...
Andrea Bracciali, Marcello Brunelli, Enrico Catald...
BMCBI
2008
122views more  BMCBI 2008»
13 years 8 months ago
A practical comparison of two K-Means clustering algorithms
Background: Data clustering is a powerful technique for identifying data with similar characteristics, such as genes with similar expression patterns. However, not all implementat...
Gregory A. Wilkin, Xiuzhen Huang
BMCBI
2008
122views more  BMCBI 2008»
13 years 8 months ago
Generating samples for association studies based on HapMap data
Background: With the completion of the HapMap project, a variety of computational algorithms and tools have been proposed for haplotype inference, tag SNP selection and genome-wid...
Jing Li, Yixuan Chen