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BMCBI
2008
13 years 8 months ago
2008
Background: Modelling proteins with multiple domains is one of the central challenges in Structural Biology. Although homology modelling has successfully been applied for predicti...
BMCBI
2008
13 years 8 months ago
2008
Background: Prediction of disulfide bridges from protein sequences is useful for characterizing structural and functional properties of proteins. Several methods based on differen...
BMCBI
2008
13 years 8 months ago
2008
Background: Tight clustering arose recently from a desire to obtain tighter and potentially more informative clusters in gene expression studies. Scattered genes with relatively l...
BMCBI
2008
13 years 8 months ago
2008
Background: There has been recent concern regarding the inability of predictive modeling approaches to generalize to new data. Some of the problems can be attributed to improper m...
BMCBI
2008
13 years 8 months ago
2008
Background: Computational discovery of motifs in biomolecular sequences is an established field, with applications both in the discovery of functional sites in proteins and regula...