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BMCBI
2008
83views more  BMCBI 2008»
13 years 9 months ago
Prioritization of gene regulatory interactions from large-scale modules in yeast
Background: The identification of groups of co-regulated genes and their transcription factors, called transcriptional modules, has been a focus of many studies about biological s...
Ho-Joon Lee, Thomas Manke, Ricardo Bringas, Martin...
BMCBI
2008
132views more  BMCBI 2008»
13 years 9 months ago
Computational cluster validation for microarray data analysis: experimental assessment of Clest, Consensus Clustering, Figure of
Background: Inferring cluster structure in microarray datasets is a fundamental task for the so-called -omic sciences. It is also a fundamental question in Statistics, Data Analys...
Raffaele Giancarlo, Davide Scaturro, Filippo Utro
BMCBI
2008
142views more  BMCBI 2008»
13 years 9 months ago
Identification of biomarkers for genotyping Aspergilli using non-linear methods for clustering and classification
Background: In the present investigation, we have used an exhaustive metabolite profiling approach to search for biomarkers in recombinant Aspergillus nidulans (mutants that produ...
Irene Kouskoumvekaki, Zhiyong Yang, Svava Ó...
BMCBI
2008
169views more  BMCBI 2008»
13 years 9 months ago
A comprehensive comparison of random forests and support vector machines for microarray-based cancer classification
Background: Cancer diagnosis and clinical outcome prediction are among the most important emerging applications of gene expression microarray technology with several molecular sig...
Alexander R. Statnikov, Lily Wang, Constantin F. A...
BMCBI
2008
71views more  BMCBI 2008»
13 years 9 months ago
Examining the significance of fingerprint-based classifiers
Background: Experimental examinations of biofluids to measure concentrations of proteins or their fragments or metabolites are being explored as a means of early disease detection...
Brian T. Luke, Jack R. Collins