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BMCBI
2008
133views more  BMCBI 2008»
13 years 9 months ago
A Web-based and Grid-enabled dChip version for the analysis of large sets of gene expression data
Background: Microarray techniques are one of the main methods used to investigate thousands of gene expression profiles for enlightening complex biological processes responsible f...
Luca Corradi, Marco Fato, Ivan Porro, Silvia Scagl...
BMCBI
2008
138views more  BMCBI 2008»
13 years 9 months ago
Inference of haplotypic phase and missing genotypes in polyploid organisms and variable copy number genomic regions
Background: The power of haplotype-based methods for association studies, identification of regions under selection, and ancestral inference, is well-established for diploid organ...
Shu-Yi Su, Jonathan White, David J. Balding, Lachl...
BMCBI
2008
106views more  BMCBI 2008»
13 years 9 months ago
Searching for evolutionary distant RNA homologs within genomic sequences using partition function posterior probabilities
Background: Identification of RNA homologs within genomic stretches is difficult when pairwise sequence identity is low or unalignable flanking residues are present. In both cases...
Usman Roshan, Satish Chikkagoudar, Dennis R. Lives...
BMCBI
2008
77views more  BMCBI 2008»
13 years 9 months ago
SeqAn An efficient, generic C++ library for sequence analysis
Background: The use of novel algorithmic techniques is pivotal to many important problems in life science. For example the sequencing of the human genome [1] would not have been p...
Andreas Döring, David Weese, Tobias Rausch, K...
BMCBI
2008
107views more  BMCBI 2008»
13 years 9 months ago
Extended Newick: it is time for a standard representation of phylogenetic networks
Background: Phylogenetic trees resulting from molecular phylogenetic analysis are available in Newick format from specialized databases but when it comes to phylogenetic networks,...
Gabriel Cardona, Francesc Rosselló, Gabriel...